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ROS are extremely reactive chemicals that comprise free radicals (such as superoxide anion, O 2 ), non-radical species (such hydrogen peroxide, H 2 O 2 ), and hydroxyl radicals (OH) (Bugger and Pfeil, 2020)

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Thus, we measured TrB1-3 distribution in B cell-specific Gclc -deficient mice and found that TrB1 were increased in Gclc -deficient mice compared to controls (Supplementary Fig

Ethics statement The study was performed in accordance with the ethical standards of the Declaration of Helsinki and its later amendments

Significantly elevated MDA levels have been found in melanoma tissues compared to control samples [109]